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Reactome, June 2011

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Update Date : 21-June-2011

Version 37 Released

Posted on June 21, 2011, 10:00 am, by Robin Haw, under Reactome Release Announcement.

Version 37 includes the new pathway topic Amyloids. Topics with new or revised events include:

Immune System (NLR signaling pathways and Class I MHC mediated antigen processing & presentation),

Synaptic Transmission (Voltage gated K+ channels), Gene Expression (Zinc Finger transcription factors),

Metabolism of amino acids and derivatives (Methionine salvage pathway), Metabolism of RNA (Nonsense-Mediated Decay),

and Biological oxidations (Glutathione synthesis and recycling).

R Stephan is our external authors in this release. P Cohen, T Elliot, E James, T Kufer, G Neu-Yilik, G Perry, F Rauscher, and J Schimenti are

our external reviewers. Three summer students are working with Reactome developers as part of

the Google Summer of Code (GSoC) 2011 program. Two recent publications describe

prognostic markers and potential therapeutic targets in adenocarcinoma and

a therapeutic strategy targeting amplified FGF19 in liver cancer by oncogenomic screening.